Entering edit mode
10.5 years ago
andreagarcia871
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60
I have an input DNA sequence with read errors (bases appear as [A/G] for example). I have also a multiple sequence alignment of all current alleles reported for a gene in a specific region of interest.
Now I want to find which combination of alleles in the MSA explains the combination of polymorphisms in my input sequence. Is there a software or reported algorithm for such task?