So I have some GFF3 files, and I want to serve them as DAS. Any suggestions?
Preferably not using BioPerl, as I didn't have that much fun last time I used BioPerls GFF3 parser and it goes OOM pretty dam quickly.
I have used GBrowse as a DAS server - It is relatively easy to set up (especially if you are already using GBrowse). I must admit that it is based on BioPerl. I usually populate the GBrowse database with bp_seqfeature_load.pl script which seems to work well for the data that I deal with.
It's difficult to get past Perl when it comes to DAS servers. There are some suggestions at BioDAS.org. LDAS is a lightweight option, but quite old and does not support newer DAS features. I would also recommend MarkF's suggestion of GBrowse as a DAS server. GBrowse + Bioperl is much easier to set up than it used to be and certainly no "worse" than comparable, complex frameworks, regardless of language.
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Not sure if this helps, so I am adding it to comments. Have you looked at DAS servers like Perl based Prosserver or BioJava based DAZZLE ? sanger.ac.uk/resources/software/proserver biojava.org/wiki/Dazzle
Have you looked at DAS servers like Perl based Proserver or BioJava based DAZZLE ?
Not sure if this qualify as an answer, so I am adding it to comments. Have you looked at DAS servers like Perl based Prosserver or BioJava based DAZZLE?