chipseq and RNA-seq expression relation

Question

[kanwarjag]

I have basic understanding of Chipseq and RNA seq data and underlying biology, However, I am trying to understand is there a rule of thumb or standard relation if we perform chipseq and RNA seq (hor known TF). I mean RNA seq targets which are enriched in Chip seq will show upregulation or it can not be generalized. Any help in pointing to a previous discussion/ literature will be helpful.

Thanks

[EvoGen]

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Answer 1

[Ido Tamir]

This can not be generalized. One tool to check for associaton of TF-binding / RNA-Seq and target genes is http://cistrome.org/BETA/

Pubmed search for TF-activity you should be able to do yourself.