SNP genotyping for few SNPs over 500 samples

Question

[hosseinv]

Hi,

I was wondering if someone could tell me about a recent SNP genotyping method for FEW snps but over fairly large (500) samples.

I did some whole genome sequencing in the past few months where I used Illumina preps protocol for that, but have no idea about methods for genotyping only few SNPs ?

Is TaqMan good for this purpose?

I thank anyone who could give me some clue on new genotyping ideas.

Best, Hossein

Answer 1

[Floris Brenk]

Taqman is a good method to genotype single SNPs, only if you want doing 500 this can be a lot of work if you have a lot of samples. OpenArray where you can genotype a lot of SNPs at the same time. You can read more about it here.

[hosseinv]

Thank you Floris. Your confirmation help me get on proceeding with my application.

Appreciated.

Best, Hossein