Question

Assembly With Two Ngs Technologies

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13.3 years ago

Cprietos ▴ 20

I am searching for methods or algorithms for the assembly process that can combine sequences from two NGS technologies (for example 454 and Illumina). Any ideas about this problem?

assembly next-gen sequencing • 2.2k views

ADD COMMENT • link updated 13.3 years ago by Cprietos • 0 • written 13.3 years ago by Cprietos ▴ 20

score 1 · Answer 1 · 2011-07-29

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Eric Fournier ★ 1.4k

MIRA does hybrid assemblies. It's open source, so if the associated paper does not describe the algorithms it uses, then you can always dig into the source code to find out.

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Ram · Answer 2 · 2011-07-29

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Jeremy Leipzig 22k

This is very much a holy grail of assembly, since the errors and depths between the two technologies differ so much.

A Question About Hybrid Assembly

ADD COMMENT • link updated 5.2 years ago by Ram 44k • written 13.3 years ago by Jeremy Leipzig 22k

score 0 · Answer 3 · 2011-08-01

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Cprietos • 0

Thanks for the replies. I will try using MIRA.

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