Eqtl Analysis Of Snps And Cis- Or Trans-Related Genes
0
0
Entering edit mode
13.3 years ago
J.F.Jiang ▴ 930

Hello friends,

recently I want to have a look at relationship between some disease related SNPs and genes. It is mentioned in some papers that genes found in GWAS may be not the right one that really the casual gene or related gene. So the eQTL method should be applied to find the real ones.

Here I have collected some SNPs and those in LD with them. And I want to get all genes in "eQTL relationship" with them.

I have checked two references providing eQTL databases, but bad results have been obtained when LOD>=6 is applied.

Is there any other database I can use? Or could you offer me a better way to reach my goal?

Thank you very much!

eqtl snp gwas • 3.9k views
ADD COMMENT
0
Entering edit mode

I tried to fix up the text in the question - I hope I understood everything correctly. Could you please provide the two references for the databases that you have already checked?

ADD REPLY
0
Entering edit mode

these are two commonly cited refs.

A genome-wide association study of global gene expression, Dixon et al,, Nature Genetics 39, 1202-1207 (2007). (mRNA_bySNP_browser_v1.0.1)

Population genomics of human gene expression, Stranger et al., Nature Genetics 39, 1217-1224 (2007).

ADD REPLY

Login before adding your answer.

Traffic: 1076 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6