Pathways interactions between two cell types

Question

[etarisal]

Hi all,

I am analyzing two different cell types, by RNAseq, which should interact each other. I have done the DE analysis and I know the set of specific genes for each cell type. Now, I would like to identify which of these genes (for one cell type) may interact with the other cell type (like ligand-receptor interaction for example). Do you know any tool that can perform this analysis?

Thanks in advance

Answer 1

[Chris Evelo]

You could perform regular Gene Ontology analysis or pathway analysis and then look up the classes and pathways that are involved in cell-cell communication.