Hello, How We Can Convert Human Entrez Gene Ids Into Mouse Gene Ids

Question

[Isar]

Hello,

How we can convert Human Entrez gene IDs into Mouse gene IDs?

Isar

[Neilfws]

You can't - they are two entirely different things. Now, if you're asking how to find the mouse orthologs of a set of human genes given the human Entrez IDs, well that's a different question ;)

[Dan D]

[Pierre Lindenbaum]

This post was changed+deleted : why ?!

can we restore a previous version of this document ?

[Michael]

Looks like it was vandalized, unfortunately I cannot see who did the last change. I have suspended the user for now in case it was him. Istvan, can you check that?

[Istvan Albert]

if modified by is not show then it is the same user as the post creator. The user may have left their account open or had their account compromised etc. the post has been restored

[bsr]

Hi Isar, you must have figure out how to convert mouse genes to human orthologos? Anyone else? tried http://david.abcc.ncifcrf.gov/summary.jsp and http://smd.princeton.edu/cgi-bin/source/sourceBatchSearch

Answer 1

[Andrew W]

Assuming, as neilfws suggests, that you are interested in finding orthologues, you can use NCBI's HomoloGene DB.

This file (ftp://ftp.ncbi.nih.gov/pub/HomoloGene/current/homologene.data) contains the mappings you need. Col2 is taxonomy ID, col3 is Entrez Gene ID.

Answer 2

[Obi Griffith]

You can also provide a list of Entrez IDs in Ensembl Biomart and get mapping from the corresponding Human Ensembl gene to the orthologous Mouse Ensembl gene. See here for an example using two Human Entrez Gene IDs (You may need to click the 'Results' button, if it doesn't load automatically). Those Ensembl identifiers can then also easily be mapped back to Entrez IDs using Biomart. Not sure if it can all be done in one query. See here for an explanation of how homology is determined by Ensembl.

[Bert Overduin]

You can add the Entrez Gene ID if you add mouse as a second dataset to the query: http://www.ensembl.org/biomart/martview/00952f77b88e24f1ac8d14cc085f170e

[Bert Overduin]

If you add Mouse a second dataset, you can also output the Entrez Gene ID: http://www.ensembl.org/biomart/martview/9a250d0adba412ad47b3c66d939e32a4

[Bert Overduin]

You can also export the Entrez Gene ID if you add Mouse as a second dataset: http://www.ensembl.org/biomart/martview/9a250d0adba412ad47b3c66d939e32a4?VIRTUALSCHEMANAME=default&ATTRIBUTES=hsapiens_gene_ensembl.default.feature_page.entrezgene|hsapiens_gene_ensembl.default.feature_page.ensembl_gene_id|mmusculus_gene_ensembl.default.feature_page.ensembl_gene_id|mmusculus_gene_ensembl.default.feature_page.external_gene_id&FILTERS=hsapiens_gene_ensembl.default.filters.entrezgene."7157,5925"&VISIBLEPANEL=resultspanel

Answer 3

[Malcolm.Cook]

I see this question was asked twice today by same person.

I answered it here: A: convert mouse genes to human ortholog