Hi,
I would like to make association study between DNA methylation data with histone methylation.
Is there a processed list of genes with H3K4me3, H3K9me3, H3K27me3 and H3K36me3 marks in promoters or gene bodies?
Hi,
I would like to make association study between DNA methylation data with histone methylation.
Is there a processed list of genes with H3K4me3, H3K9me3, H3K27me3 and H3K36me3 marks in promoters or gene bodies?
Noyk, you can use UCSC genome browser to get this data.
For example: select wanted histone modification (from "Table Browser -> Regulation -> SYDH Histone") and use intersection with Genes group.
This way is simple and quick - should work for primary investigation.
or if you have a bed peak file, you can use http://broad-enrich.med.umich.edu/ to annotate the peaks or you can download the refgene table from UCSC, get the promoter region for each gene, and use bedtools intersect with the histone modification peaks.
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Which organism? Which developmental point? Which tissue?