Hi all,
I was wondering if anyone has attempted using RNA-Seq for applications like prognostic or diagnostic classifier model generation? There are numerous examples of this being done with microarrays (e.g. Mammaprint) however I am not aware of any NGS work in the field.
Any help appreciated.
didn't we cover this?A: Next Gen Sequencing Vs Microarray Advanced Applications
What would be the conceptual difference between doing it for RNA-seq-derived as opposed to microarray-derived expression data?
Jeremy - no I don't think so. My previous question referred to both classifiers and association and I don't believe I got any answer on the classification.
Mikael - I don't know myself! I believe the concept must be pretty much the same but I'm guessing there have to be some technology-specific factors that would complicate matters. I'm trying to determine if anyone has actually attempted it.