molecular weight of the truncated protein using a 2nd AUG downstream of the normal AUG
1
0
Entering edit mode
10.1 years ago
datanerd ▴ 520

Hi all,

We have a protein where the mutation is affecting the start codon. Could someone please direct me to a tool that would help determins the second (AUG) start codon and the estimated weight of the protein.

Thanks!!
Mamta

molecular-weight protein-truncation start-codon • 2.1k views
ADD COMMENT
0
Entering edit mode
10.1 years ago
Whetting ★ 1.6k

you mean this? http://web.expasy.org/compute_pi/

ADD COMMENT
0
Entering edit mode

Thanks Whetting! This is helpful!

This is useful when I get the new sequence for the protein with the potential new start codon. How do I get the next possible start codon for the gene if the original is mutated?

Mamta

ADD REPLY
0
Entering edit mode

you can just look for the first in frame ATG? Alternatively, check out ORFfinder at NCBI

ADD REPLY

Login before adding your answer.

Traffic: 2064 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6