Negative score in TCGA pancancer gene expression data

1

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10.0 years ago

BIOTIN ▴ 50

Dear all,

I am working with TCGA pancancer gene expression level 3 data. I found that there are some genes expression levels are negative. Could anyone please tell me how the negative score generated?

RNAseq gene-expression • 2.9k views

ADD COMMENT • link updated 2.7 years ago by Ram 44k • written 10.0 years ago by BIOTIN ▴ 50

1

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Are they logged?

Log10( 0.1) = -1

ADD REPLY • link updated 2.7 years ago by Ram 44k • written 10.0 years ago by Danielk ▴ 640

0

Entering edit mode

They are logged by Log2(x+1), which should not be negative...

ADD REPLY • link updated 2.7 years ago by Ram 44k • written 10.0 years ago by BIOTIN ▴ 50

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