Help with-- Cytoscape- ClueGO- Bingo
0
0
Entering edit mode
9.8 years ago
friasoler ▴ 50

Hello .-) is someone here familiar with Cytoscape and the apps bingo and cluego?

I'd like to build a good network with the list of genes. Thanks in advance

Roberto

RNA-Seq • 4.0k views
ADD COMMENT
0
Entering edit mode

It is a bit vague as question. More details you provide more precise will be the help you are going to get.

ADD REPLY
0
Entering edit mode

Yes you are right. The point is I cant build the network the app ClueGO say there is no terms associated with the list I'm given. Actually the list came from an heterogeneous annotation means gene names from different organisms:

GLOD5_HUMAN
AVR4_CHICK
INHBC_MOUSE
ACBG2_RAT
ACBG2_RAT
CHIA_MOUSE
EMP2_HUMAN
LEAP2_MACMU

I tried also with out the organism name and using just the names annotated from the same organism. Then if you have any suggestions for me I'll appreciate!

This an example list I'm using:

LC7L3
RPGF5
C1TM
ACOC
PIPNA
G1N0K7
PDP1
ARSD
EGLN1
PLPL2
PANK3
RANB9
PDE8A
DMA
RD3
RHG12
SYDE2
H0ZSE4
DHRS7
P3IP1
G1MUM5
BAG3
BGB
LIPL
HRSL3
MFS2A
AQP9
COX1
SIAT9
ANTP
ENPL
BTD
MCF2L
NFIL3
RGS12
CP2C9
CLIC5
GFPT2
KI21A
MYO10
CDCA7
NLTP
ARHG4
RYK
CP4V2
S4A11
G1NMN2
ABHD3
NACAM
MOT9
PIM3
G1MW53
ZNT1
NOGG
NOCT
G1N6M5
LPP3
G1N750
CTL3
LPAR4
DSA2B
CP4F5
TBCD1
CIDEA
SPON2
CHAC1
LPIN1
G1N2T8
ADR1
RYK
AL1A3
ARRD2
MA1A1
MAFB
LAMB4
TBCD1
SEM5A
MSMB
BIP3
MET7A
G1N7F8
LPHN3
AT2L1
G1N306
NFASC
IFT80
H1A409
SEM5A
G1NRJ0
ZNT1
TNNI2
RGF1B
ARGI2
ARHG3
IP6K2
SYNE1
G1N750
CSEN
MERTK
EMIL2
UAP1
EMSA1
PDPFL
ITA6
CP2U1
CP7B1
CITE2
ENV
IBP3
ATF3
GA45G
LPIN1
G3USV5
MOT10
B5FY13
G1MQI4
MX1
KLK14
RSLBA
ADD REPLY
0
Entering edit mode

ClueGO uses GO term, I think the problem is that you organism (or mix of them) is not in their DB. I guess this are orthologous protein among the organisms. If this is the case You can fix this selecting one among Human, Mouse etc. On the other hand you could us a Bioconductor package where you can provide your gen set and you background set, both previously annotated with GO. I really like GOstats and topGO

ADD REPLY
0
Entering edit mode

It would be nice if you add such a long list as external link..;)

ADD REPLY
0
Entering edit mode

Oh thanks for your answer. I'm not familiar with R. I'm just starting in this stuff I know Bioconductor and its power but that a limitation I have right now. Thanks anyway

ADD REPLY

Login before adding your answer.

Traffic: 1928 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6