Alternative to MrBayes for BI phylogenetics?
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9.7 years ago
confusedious ▴ 490

I am doing some work that involves comparing different phylogenetic methods and I am having some trouble finding a suitable tool for Bayesian phylogenetics.

I have Geneious and the MrBayes plugin that goes along with it, but it only runs on a single thread and as such is ponderously slow. I have also installed the Linux version of MrBayes along with the extra components needed to use multithreading with it.

The issue with this version of MrBayes is in the fact that it uses a non-standard nexus file format. This is something of a two-fold issue for me. First, the rest of my pipeline uses fasta format and switching file formats back and forth unnecessarily complicates things (and introduces a small chance of accidentally altering the data). Second, the version of nexus used by MrBayes is a non-standard one, which means that none of my existing export tools will adequately handle this.

Is anyone aware of an alternative Bayesian phylogenentics tool? Preferably one that uses fasta?

phylogenentics MrBayes Bayesian • 4.1k views
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Does MrBayes use a "non-standard" nexus? I thought it was nexus with the option of a "MrBayes block" containing commands? I've always written nexus files for MB with Biopython and had not problems.

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Interesting... Maybe it's Geneious that is writing odd nexus files then. I'll take a look at this.

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9.7 years ago
apelin20 ▴ 480

you can compile mpi version of mrbayes.... there is also phylobayes and beagle/beast

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I have compiled the MPI version, it runs on mulitple threads fine. It was only the Geneious plug in that doesn't.

I'll check out phylobayes and beagle/beast as well.

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9.7 years ago
5heikki 11k

PhyloBayes. There's also a MPI version..

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