Any tools for predicting protein solvent exposure/accessibility?

Question

[fr]

I am looking for some bioinformatics tools that can take some 1000 proteomes and predict aminoacid exposure to solvent from the protein sequence.

I know there are caveats, and that such prediction is hardly accurate, but still...

Many thanks

Answer 1

[dago]

J. Cheng, A. Randall, M. Sweredoski, P. Baldi, SCRATCH: a Protein Structure and Structural Feature Prediction Server, Nucleic Acids Research, Web Server Issue vol. 33, 72-76, 2005

http://download.igb.uci.edu/sspro4.html

[fr]

thank you very much!

[fr]

if someone has other tools I'd appreciate it, as I'm running many many sequences and having other tools to compare may help