Predicting Protein Disorder Using Metaprdos

Question

[Elmo]

Hi,

I'm using metaPrDos to predict protein disorder. The result I obtained from the email output which indicates the two-state prediction of * as disordered and '' as ordered compared to the html formatted output of "red" as disordered and "black" as ordered is different. For instance, at this site (http://prdos.hgc.jp/meta/usage.html) where residue number 10 (E) and 11 (V) is not marked with an asterisk meaning that it is ordered, however at the HTML formatted output shows that residue 10 and 11 is in red, indicating it as disordered. Please correct me if I got the idea wrongly. :(

Thank you for your advice.

Answer 1

[ALchEmiXt]

My best guess from it is that they just show an example but that the settings for the example output html (on apparently the same sequence) was different (probably a different false positive rate). Thereby the examples not entirely match up.

If you run their service on this sequence you should get the definitive answer! When I run it on 5% FP rate I get the results from the html example (also correctly in mail).