Question

how to determine the interacting genes

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9.7 years ago

Sabine ▴ 70

Dear Friends,

I am working with histone proteins in my new project. I am trying to determine the genes interacting with HDAC11 gene. ultimately looking for genes various pathways leads to cancer. is there any good webservers or databases I can look for sorting out the genes for this study?

Thanks for reply

genes-interaction pathway histone-proteins • 1.9k views

ADD COMMENT • link updated 2.5 years ago by Ram 44k • written 9.7 years ago by Sabine ▴ 70

Ram · Accepted Answer · 2015-04-15

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9.7 years ago

HG ★ 1.2k

Hi sana,

Please have a look in " string" database. Here you need to chose specific organism to see the interacting gene.

http://string-db.org/

ADD COMMENT • link 9.7 years ago by HG ★ 1.2k

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as far i know, it gives the interaction with modelled or existing protein structures only..still i will be able to check again. thanks for the valuable reply..cheers

ADD REPLY • link 9.7 years ago by Sabine ▴ 70

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Yes it will show you only existing protein in DataBase. If you have some background information about metabolic network then you can also try in any network visualization tool such as "Cytoscape"

ADD REPLY • link updated 2.5 years ago by Ram 44k • written 9.7 years ago by HG ★ 1.2k

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How about BioGrid..any idea? please share..thanks

ADD REPLY • link 9.7 years ago by Sabine ▴ 70