microarray data sets

Question

[bioinfo]

I collected 3 datasets with different platforms. My interest is to find out target genes using bioinformatics tools and some data mining approaches. But i am little bit confuse on how to validate my result without wet lab approaches..???

[bioinfo]

Thanks... If possible Can you please refer me some journal on that ????

[Devon Ryan]

Perhaps you can find a review article somewhere, this is more the sort of thing you'd find in a text book.

Answer 1

[Devon Ryan]

Your options are:

1. Find a dataset with known positive/negative results and run that through your prediction to see how close the results are.
2. Do cross validation (or similar), though you might need more datasets.

Option 2 isn't really validation in the strictest sense, but it's as close as you can get without additional experiments.