Differential Methylation Analysis

Question

[enricoferrero]

Hi,

I've just started working in this area and am looking for some pointers.

What software packages does the community use for the analysis of differentially methylated regions from WGBS data?

I used Bismark to perform the alignment and the methylation calling steps.

Thanks!

Answer 1

[Evgeniia Golovina]

You can also use Bsmap and methratio tools.

Answer 2

[hongbo919]

Hi, we have developed a new software for de novo identification of DMRs from various BS-Seq data including WGBS. Maybe it is useful for you. http://fame.edbc.org/smart/ Best wishes! :)