Question

question about NIH Epigenome roadmap neural differentiation data

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9.5 years ago

weihsianghuang • 0

I've been trying to find the histone modification/RNA-seq/DNA methylation data of the Epigenome roadmap project from http://www.roadmapepigenomics.org/data/

I can't find some of the data described in "Dissecting neural differentiation regulatory networks through epigenetic footprinting", which is the data from ES cell differentiate into Neuroepithelial, and then Early Radial Glial, and Mid Radial Glial cells.

According to the Nature paper they seemed to deposited all their data onto the roadmap website, can anyone help me to find them please?

Thank you

WH

roadmap neuron epigenetics • 2.3k views

ADD COMMENT • link updated 23 months ago by Ram 44k • written 9.5 years ago by weihsianghuang • 0

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Hello!!! I am trying to find out in road map epigenomics regarding the brain cancer. So, could you please tell me which one is cancer, normal counterparts in brain cancer which is embedded in epigenomics roadmap.. Please help me to find out...

ADD REPLY • link updated 5.1 years ago by Ram 44k • written 9.5 years ago by arpa530 ▴ 20

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As far as I know road map consortium didn't collect epigenomic data from cancer. If you are referring to Polak et. al. 2015, they analysed published datasets and compared with the roadmap (normal epigenome) data.

ADD REPLY • link updated 23 months ago by Ram 44k • written 9.5 years ago by vivekbhr ▴ 700

Ram · Answer 1 · 2015-06-01

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9.5 years ago

vivekbhr ▴ 700

Hi

Search for the H9 cell line and their differentiated counterparts. Most of the datasets you are probably looking for is here.

Hope this helps.

ADD COMMENT • link updated 23 months ago by Ram 44k • written 9.5 years ago by vivekbhr ▴ 700

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Thank you Vivek!

ADD REPLY • link 9.5 years ago by weihsianghuang • 0