A very simple question I guess: In a sam/bam file I notice there may be several "libraries" of inserts (LB tag). Could you explain to me where do these different libraries come from in the sequencing process? And/or give me some examples that lead to production of several libraries. Thanks.
Thanks Chris! I really did my homework googling and reading other sequencing related documents before asking this question but I could not find easily the explanation of this. Thank you for the synthesis, this is very clear.