the possibility of Lositan for big data (600K)?

Question

[snowy]

Hi,

I'm using Lositan for selection analysis and my data is whole genome-wide SNPs about 600K. Given for the limit of the large marker version, I could only calculate it for each chromosome. But I think the result maybe not reliable.

So my questions are:

1. Is there a new version for big dataset?
2. What limited the number of markers, RAM or others?
3. Is it possible for big data after modification?

Thank you!

[Zev.Kronenberg]

If you're looking for Fst: https://github.com/jewmanchue/vcflib/wiki/Association-testing-with-GPAT