What parameters should the LD LOD and D' have?
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9.5 years ago
Danielson ▴ 40

I downloaded the HapMap LD files, and am generating SNP data based on MAFs.

In order to complement the generated SNPs, I'm using the LDs. So now I have a list of SNPs for which HapMap has information on LD, LOD and D-prime. But not all values in these files appear helpful, for instance when LOD is <1 - no negative values in dataset).

I need a set of parameters to decide which LDs to use, and which to ignore.

Does anybody know whether there as consensuses on cut-off values for these variables?

LOD LD HapMap D-prime • 2.7k views
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