dbSNP 144 for Annovar

Question

[Ishtiaq Ahmad Khan]

I am using annovar for human genome annotation. I want to use dbSNP 144 as my alignment is on build hg38.2. I am wondering which file from dbSNP ftp I need to download. Secondly, Annovar uses txt format of dbSNP. How can I format my dbSNP 144 files.

Answer 1

[Ishtiaq Ahmad Khan]

I have tried different options and bcftools annotate worked. I used vcf file of dbSNP 144 on hg38.2.

bcftools annotate -a dbSNP_144.vcf -c ID -o output.vcf input.vcf