How to search conserved protein domains?

Question

[biolab]

Hi, everyone,

I used SMART website (http://smart.embl-heidelberg.de/smart/set_mode.cgi?NORMAL=1) to search if there exists conserved domains or motif for my aim protein. However, I did not get any information from SMART analysis. I am wondering if there is any other webtool to perform similar analysis? THANKS A LOT in advance.

[venu]

Did you check Conserved domain database.

[biolab]

Thank you venu. Although I got no hits, your site is really useful.

Answer 1

[kaihami]

If got your question, you can use PSI-BLAST or HMMER