NCBI gene IDs

Question

[sharma_tina189059]

Hi can anyone tell me why I am getting duplicate gene Ids in NCBI...The same gene Id exist several time..what is the reason behind this?

[roy.granit]

Please supply an example of such ID

[zizigolu]

did you map against the proper organism?

[Neilfws]

You need to explain what you are doing more precisely, when you say "getting" and "exist". Getting from where and how?

Answer 1

[matt.newman]

We've found there are some genes that have the same name, but on different chromosomes. Not sure if this is what you are referring to or not.

[GenoMax]

Post examples please.

[roy.granit]

Please write here the gene ID number

[matt.newman]

http://www.ncbi.nlm.nih.gov/gene/3581

Found on both X and Y chromosomes.

Another one: http://www.ncbi.nlm.nih.gov/gene/653440

I thought we found some others previously, but those are the quick ones I could dig up. We have a tool for building custom gene model (transcript libraries) in our Array Suite package, and we had to build in some special logic for some counting algorithms.

[GenoMax]

I think these genes have their origin in the evolution of the Y chromosome. There is an interesting video on this site that explains the process: http://www.hhmi.org/biointeractive/evolution-y-chromosome

Some other genes around WASH6P are present on both X and Y chromosomes.

[Neilfws]

Interesting, I was not aware of this. I recommend users read the Gene FAQ. It includes a section named "Multiple chromosomal locations", although what they describe there relates to annotation merges rather than the example of Gene 3581.

[sharma_tina189059]

yes..u were right..thanku

Answer 2

[sharma_tina189059]

i got the answer guys...the same genes were present on chromosome and plasmids that z y ncbi mentioned same gene ids several times