Disease pathway prediction

Question

[aisha.comsian]

HI, I am doing pathway prediction of a disease using multiple tools available like IPA, genemania and others. i have more than 400 genes identified as co expressed genes with my identified candidate genes. now i want to design own predicted pathway how these genes are linked with each other. i heard about metacore pathway creator but its not freely available. can anyone please tell me alternative for it where i can draw organelle wise genes and a symbolic pathway..

Answer 1

[Antonio R. Franco]

Take a look to

• PATHiVAR
• Babelomics

[aisha.comsian]

actually I do not have ngs data... I did gene prioritization through many available tools and then pathways analysis of these candidate genes using IPA free trial. then I searched for co expressed genes for candidate genes through coexpressdb. on the basis of this info I want to draw a pathway for a disease

Answer 2

[Mary]

Oh, I just saw something that gives you organelles and other graphics, and you can put it on your own custom pathways. PathWhiz.

I wrote about it here: http://blog.openhelix.eu/?p=22292 and the next week's tip had more details on drawing: http://blog.openhelix.eu/?p=22433.

You can go directly to it here: http://smpdb.ca/pathwhiz