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13.0 years ago
Shigeta
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470
Does anyone know of a good set of ChIP-ChIP data for bacterial chromatin-DNA binding?
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Prokaryotes don't have histones and therefore such data cannot exist. http://www.nature.com/scitable/topicpage/dna-packaging-nucleosomes-and-chromatin-310
Prokaryotes don't have histones and therefore such data cannot exist.
Actually, archaea have histone-like proteins; see e.g. http://www.ncbi.nlm.nih.gov/pubmed/9783158. Bacteria don't have nucleosomes, but ChIP methods have been applied to them; e.g. http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2958.2007.05781.x/full.
Yes, but that was not the question asked; the modified question is a different and much more general topic than @shigeta originally posed.
chromatin is just a level of histone organization that is apparently only evident in eukaryotes. i am not sure if the chromatin structure is even characterized. maybe that's a good question for someone to put up.
ok changed all reference to chromatin.