Simulating Cnv Into Genome Reference

Question

[chico.nascimento]

Hi everybody, I´d like to know if someone has some hint to simulate introducing CNVs into genome reference in way as near to actual as possible. Thanks in advance.

[Leandro Lima]

Hi Chico.

I'm trying SCNVSim. Did you find any other tools?

Thanks

Answer 1

[PoGibas]

I recommend PEMer (Gerstein lab).
PEMer has SV-simulation tool which lets you to specify CNV information you want (CNV type, size, how many).

Answer 2

[Leandro Lima]

I'm using RSVSim, now. For me, it was the best and easiest to use, so far.