Pathway analysis using protein content (weight%)

Question

[robjohn70000]

Hi,

I'm new to proteomics. I wonder if it is possible to carry out pathway analysis on protein content (weight%) data from proteomics experiments. I have a list of genes and their corresponding protein content (weight%) for a number of conditions(control and test). I'm actually interested in the differential expression of test/control, supported by P-value, so that I can determine significantly perturbed pathways. Would normalization and ranking be useful? Which tools in R maybe useful for the pathway analysis? Can anyone suggest the correct approach for doing this analysis.