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9.1 years ago
Biomonika (Noolean)
3.2k
Hello, I am trying to find where to download human alpha satellite sequence. So far I have only been able to find one from 1987 paper: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC306152/pdf/nar00260-0438.pdf
I know that Karen H. Miga incorporated her Centromere Reference Models into GRCh38, so downloading her predicted sequences of centromeres would also be helpful - if you can point me where to download those. However, alpha satellite (or multiple since they are variable) would be the best.
Thanks, I downloaded RepBase20.10.fasta.tar.gz and tried to search for "alpha" and "satellite" with no success.
I'm not sure what that file shows but it looks like a random mix of repeats from different organisms. It could be just an update file without original data.
Try going to http://www.girinst.org/repbase/update/browse.php
Then select "Satellite" under the Repeat Class drop-down menu
Then select "Homo Sapien" under the Taxon drop-down menu.
This will give you an option to browse or download all human satellite and/or primate satellite sequences.