Tool:THOR a HMM based approach for differential peak calling with replicates

Question

[vanvanka]

Dear all,

It is a pleasure to inform the release of THOR a HMM based approach for differential peak calling with replicates.

www.regulatory-genomics.org

THOR provides all pre- and post-processing steps required in ChIP-seq: analysis including: fragment size estimation, input-DNA normalization, GC-bias correction, normalization of replicates, p-value estimation, multiple test correction and strand lag filtering of potential DPs.

best,
Ivan

[Ben]

Could you explain the THOR in detail?

[Carlo Yague]

Link to the THOR paper.

Answer 1

[Ian]

I see the "paper release" version, but cannot find the paper. Is it still in-press?