Is it possible to get seq data for cancers via database?

Question

[gooshiroy]

I am looking for resources to download actual sequence data in terms of nucleotide arrays for certain cancer mutations. Are there any databases available to do so by filtering specific cancers and genes? I am looking for something akin to the regular vanilla NCBI website. However, the gene sequences of interest at the NCBI are not of cancer genes. For example, I can only get a regular vimentin protein sequence, not a mutated gene sequence from a specific brain glioblastoma case or a prostate cancer case, etc.

EDIT: I am an undergraduate student and I cannot access UCSC's Cancer Genomics Hub.

Answer 1

[Cyriac Kandoth]

Ensembl's Variant Effect Predictor (VEP) has a plugin that generates a FASTA file containing mutated mRNA sequence. It will only do this for one mutation at a time. If this is what you want, you can find what you need here and here.

If you provide more info on the experiment you're trying to perform or the specific biological questions you're trying to answer, I can expand this answer to be more helpful.

Answer 2

[Benn]

Did you check The Cancer Genome Atlas? There is a lot of data available in their resources.

http://cancergenome.nih.gov/

[gooshiroy]

They say that do not have lower level seq data. Higher order data needs to be acquired via dbGap