EGFR and KRAS expression

Question

[aj123]

im trying to find out up and down regulation of EGRF and KRAS in colorectal cancer. im looking for some rna-seq data for the same. any suggestions on some good data sets?

Answer 1

[David Quigley]

If you don't specifically need RNA-seq data, there's a very large amount of retrospective transcriptome data on GEO, e.g.

http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE40967
http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE68468
http://www.ncbi.nlm.nih.gov/gds/?term=colon%20cancer

You could look into this Genentech paper with "70 pairs of primary human colon tumours", but I don't know about data availability.

http://www.nature.com/nature/journal/v488/n7413/abs/nature11282.html