Mirna Pdb Structures

Question

[Repsy]

Hi all,

I want to get all the miRNAs PDB structures from PDB. But When i do advance search in PDB, it gives me only 1 structure. SO, could anyone suggest me some database of miRNA from where i can download all the available PDB structures or all the miRNA structures from PDB?

Thanks in advance

Answer 1

[Neilfws]

You could try "Macromolecule Type" in advanced search and select "Yes" for RNA and "No" for the other options. You could also specify number of chains = 1 and select maximum/minimum lengths ("Chain Length") for typical miRNAs.

However, you'll have to do some manual filtering of the final result set, since "miRNA" does not seem to be a common annotation in the PDB.

It may also be that there simply are not very many miRNA structures (and they are likely to be solution NMR, rather than crystal structures).