Entering edit mode
9.0 years ago
toyan.j.p
▴
30
Hi,
- I would like to know how analysis with TRAP is different from linear regression for quantitative traits? I tried both with a data of 49 variants in a sample of 50 individuals. Is it advisable to do TRAP when you are analysing only cisQTLs? I tried both and there are differences in results obtained, though some are common
- Another query is in the final results from TRAP, there is a section lists P values-what are they?
e.g.: 8.207e-08, 2.491e-04 and 6.771e-04
PREDICTORS IN SELECTED SET (MAIN EFFECTS ONLY):
______Single_______ __Genome-selected__
Predictor Chr Position Tile / N P \ / N P \
================================================================================
50 8.207e-08
++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++
snp1 X 136494594 A6 50 2.491e-04 6.771e-04
snp2 X 136499412 A25 50 1.024e-02 2.001e-03
snp3 X 136500515 A29 50 1.859e-04 7.932e-03
snp4 X 136523847 A45 50 7.188e-03 3.646e-03
FITTED MODEL (MAIN EFFECTS ONLY):
serum =
( 6.20248)
+ ( 24.9027) x snp1
+ ( 15.7717) x snp2
+ ( 10.3505) x snp3
+ ( 13.0561) x snp4
What are the terms in parenthesis? Are these beta values?
Thanks in advance for any help
Regards
Toyanji