What can I do with the genome-wide operon predictions?
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8.9 years ago
2351688559 ▴ 20

Hi!

I 've retrieved the genome-wide operon predictions of some bacterial genomes from DOOR 2.0 database, but I really don't know what can be done with those tables. I've been traped here for serveral months and my boss is very angry about this. Anybody can provide a way out?

Thanks!

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May I ask why you retrieved those predictions without having a goal of what to do with them? You've got to provide more background information if you want to see some help. The more detailed information the easier it is for everyone else to provide help.

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Thanks for giving a comment!

The genomes belong to 4 strains of the same species, Acetobacter pasteurianus, a kind of acetic acid bacterium used for brewing vinegar. The original goal of the work was to conduct a genome-widely comparative analysis of operons through the 4 strains. Their differences in their operons were surely detected, but it was quite difficult to find relationships between the differences in operons and the strain's individual performances in fermentation, since the key genes that were proposed in the literature were found well conserved among the 4 strains, as well as the operons that contain them. Thus, I found difficult to draw conclusion. Then I began to consider analyzing those predictions from other aspects, so I came up with this question. I was always told to learn what and how to do with the predictios from the literature, unfortunately, I found I am alone, nobody has done the similar work and no such literature available. I wonder if there is any idea to find a way out or any algorithm or program that is proper for the further analysis.

Thank you very much!

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