groHMM input data

Question

[dally]

I am attempting to use the groHMM package from Bioconductor to preform a metagene analysis.

I've played around with the included sample data and was able to get most of the tutorial done. However, attempting to use my own input files have proven ... errr ... well it's gone badly.

I had assumed that the input data prior to wiggle creation was bam files as specified in the vignette, but my bam file (13gb) causes an error when attempting to read in that file via Rsamtools because it's huge file size. So i'm wondering if this file type is even the correct input.

Hoping someone could help me out.

Thanks.