Trueseq Vs Nextera

Question

[MAPK]

I am trying to understand the difference between trueseq and nextera exome sequencing in terms of capture region. What is the capture size of Truseseq as compared to nextera and which one gives better coverage to identify the variants in UTR/intergenic regions?

Answer 1

[Sean Davis]

You can download the .bed files for each technology here:

• https://support.illumina.com/sequencing/sequencing_kits/nextera-rapid-capture-exome-kit/downloads.html
• http://support.illumina.com/content/illumina-support/us/en/sequencing/sequencing_kits/truseq-exome-kit/downloads.html