Question

Is there a GTEX trans-eQTL analysis?

0

Entering edit mode

8.7 years ago

Milos Pjanic ▴ 30

Has anyone done a trans-eQTL analysis using data from GTEX? Would it be feasible due to relatively lower sample numbers in GTEX compared to what is required for trans-eQTL data analysis? Thanks

RNA-Seq eQTL trans-eQTL • 2.7k views

ADD COMMENT • link updated 8.7 years ago by informatics bot ▴ 760 • written 8.7 years ago by Milos Pjanic ▴ 30

score 3 · Answer 1 · 2016-03-03

3

Entering edit mode

8.7 years ago

informatics bot ▴ 760

Cis EQTL analysis is feasible with GTEX data-sets (I've performed it successfully with approximately 237 donors).

Trans-EQTL requires much larger sample sizes and lower p-values to classify significant EQTL's. I doubt it would be feasible.

ADD COMMENT • link 8.7 years ago by informatics bot ▴ 760