QC methods for next generation sequencing samples
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8.6 years ago
MAPK ★ 2.1k

I have been trying to find some papers that discuss quality control on Next generation sequencing samples. I know a lot of paper that discuss about QC on SNPs data, but none on QC of samples. I think P-link is one of the popular tools for this. Can someone please help me find the right papers and available tools used in QC of Samples.

NGS samples • 1.5k views
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Do you mean something like FastQC or some other sort of QC?

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No, in terms of IBD and relatedness where we use these QC for correcting confounding biases, but not limited to or exactly of GWaaS studies

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No, in terms of IBD and relatedness where we use these QC for correcting confounding biases, but not limited to or exactly of GWaaS studies

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Ah, you might want to add that to your post and update the title.

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8.6 years ago

Relatedness can be studied using either ersa2.0 (http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1004144)(rather complicated) or something as simple as PCA.

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