Entering edit mode
8.6 years ago
Alejandro Jimenez Sanchez
▴
180
To convert VCFs to MAFs I use the very well documented tool vcf2maf.
In the introduction it says:
To convert a VCF into a MAF, each variant must be mapped to only one of all possible gene transcripts/isoforms that it might affect. This selection of a single effect per variant, is often subjective. So this project is an attempt to make the selection criteria smarter, reproducible, and more configurable. And the default criteria must lean towards best practices.
Is it possible to include all possible gene transcripts that might be affected?
If so, how could this be achieved?
Thanks