Human Chronic Myelogenous Leukemia cell line

Question

[kamlika]

Hi! Is there any human cell line that represents chronic myelogenous leukemia in chronic phase? The cell lines those I am finding formed from blast crises patients but not from cp. If anybody can help me with that.

Kamalika.

Answer 1

[russhh]

This is somewhat off-topic for Biostars, but... No, the only existing data from chronic phase CML is from primary samples (although there's quite a bit of it). Cells from chronic phase don't proliferate well in vitro and things like K562 etc are all from blast crisis