is there anyway to investigate a specific pathway

Question

[Learner]

Hello,

I would like to know if there is any way that I check for a specific pathway using my gene list ?

I have a list of genes which are unregulated and I only want to check if a specific pathway is activated or not

Thanks

[GenoMax]

Try http://www.reactome.org/ and "analyze data". If you just want to browse then http://pathwaycommons.org/

[reza.jabal]

You may find this thread useful! Kegg Pathway Analysis

[Learner]

@reza.jabal DAVID is not the way to go, but thanks

Answer 1

[EagleEye]

Gene Set Clustering based on Functional annotation (GeneSCF)

try GeneSCF, simple command line tool accepts gene list and perform enrichment analysis in real-time (directly extract information from selected database). You can also choose between different database GO, KEGG, REACTOME.

http://genescf.kandurilab.org

Answer 2

[Ron]

Use GSEA http://software.broadinstitute.org/gsea/index.jsp I am assuming the pathway and the list of genes is same. It will give enrichment results if your pathway is upregulated or down regulated with p-values. Also you can search for your own pathways,curate your own pathways to look for enrichments in your data.