How to tell bloodtype from SNPs data?
1
0
Entering edit mode
8.4 years ago
O.rka ▴ 740

I want to check my bloodtype based on my SNPs data. I have results from AncestryDNA with ~ 668 943 SNPs. Is there a website I can go to to import the data and get this phenotype?

Format of my data:

rsid    chromosome  position    allele1 allele2
rs369202065 1   569388  G   G

Each line corresponds to a SNP. Column one provides the SNP identifier (rsID where possible). Columns two and three contain the chromosome and basepair position of the SNP using human reference build 37.1 coordinates. Columns four and five contain the two alleles observed at this SNP (genotype). The genotype is reported on the forward (+) strand with respect to the human reference.

SNP genome human analyze ancestry • 19k views
ADD COMMENT
1
Entering edit mode

SNPedia has this page which may be of interest.

ADD REPLY
0
Entering edit mode

Are you looking for a quick look-up or a lifelong career? Because you're looking for a genotype-phenotype correlation that I'm not sure exists yet.

EDIT: From genomax's link, it looks like there is quite a bit known on this topic. If the data is reliable depends on your purpose though, if you ask me.

ADD REPLY
0
Entering edit mode

It is difficult to find authoritative information on ABO. For basic bio background, I found this review very helpful.

Yip, S. P. (2002). Sequence variation at the human ABO locus. Annals of human genetics, 66(1), 1-27.

ADD REPLY
3
Entering edit mode
8.4 years ago
matted 7.8k

Promethease should work for this. They have an example report from Ancestry.com data that includes a blood type prediction (click the "Blood" tab).

There are many related web tools in this space; see http://www.23andyou.com/3rdparty for one list.

ADD COMMENT

Login before adding your answer.

Traffic: 2831 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6