Entering edit mode
8.4 years ago
Sama
▴
60
I have a few questions about bacterial populations which contain several strains of a bacterium. My background is Computer Science.
I know one of the examples of bacterial populations with very similar strains is "mixed infection" data (as this paper addressed). What are the other examples for these populations?
How many strains usually can be found in one population?
I guess two strains has about 1000-1500 variation with each other. Is that correct?
If we map the strains to the reference genome, we will find SNPs of strains. What percentage of SNPs of two strains are shared?
Is there any software for simulating this kind of data?
Is that correct to call each strain "haplotype"?
In each replication of the genome you can expect one mutation or so. Imagine what happens after hundreds of generations in a plate