how to make a network of known cluster of proteins
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8.4 years ago
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I came across to make a plot of a bunch of proteins which experimentally found to make a cluster. Lets say I have 3 clusters. Each cluster consists of a number of proteins. How can I plot all the clusters together ? (not interacting with each other but just linked through centre or something like this ?

Cluster 1: Q9Y4Y9, P62310, Q9Y4Z0, Q9Y333 ,P62312, O15116

Cluster 2: Q9Y4Y9, P62310, Q9Y4Z0, Q9Y333, O95777, P62312

Cluster 3: O14497, P51532, Q8TAQ2, Q92922, P60709, O96019

proteomics • 1.6k views
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Do you want to link the clusters if they share proteins or do you want to link them arbitrarily ?

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@Jean-Karim Heriche I don't want to share them based on their similar proteins , probably arbitrarily is the option. however sometimes they do share proteins, which makes me wonder that it would make sense to also link them through that. But then I ask myself what will happen to those clusters which have nothing in common to share with others ???

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There are plenty of other ways of linking your clusters. It all depends on what you're trying to do/show. For example, you could link your clusters based on shared GO terms or any other attribute they can have. You could also have links of different types (this is called a multigraph).

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@Jean-Karim Heriche would it be possible to give an example of first one ?

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