If I have a inteseted bacteral protein geneor it from pathogene, is there a way that I can find homogeneous protein in human through database searching?

Question

[Ivy Ng]

or its related proteins ... The protein we are targeting is gtfb that we study it's binding/ adhesion properties.

Thank you so much! Ivy

[natasha.sernova]

As far as I have understood, you have some bacterial genes and

you would like to determine if they have some human homologs, am I correct?

This is one of the comprehensive human gene databases:

http://www.ncbi.nlm.nih.gov/genome/guide/human/

This post is close to your question to some extent:

How To Find Human And Bacteria Homologs Of S. Pombe Protein.

At least, it discusses ENSEMBLE database.

Many years ago scientists showed the following:

Homologous ribosomal proteins in bacteria, yeast, and humans.

http://www.ncbi.nlm.nih.gov/pubmed/3529092

[natasha.sernova]

You can try to do something similar, if you replace Drosofila genes to your bacterium genes.

See this post. Human latest genome release has been updated since then.

Identifying Homologues In Drosophila For Human Genes On Large Scale

[Ivy Ng]

Thank you so much, it's really helpful!