i have a vcf file,like below: chr1 98186497 . GA/+A G . PASS chr1 115251293 . G -A . PASS chr2 209103969 . G -A . PASS chr2 209110006 . TA/+A T . PASS chr2 209116299 . G -A . PASS chr7 140439756 . GA/+A G . PASS chr7 140507735 . C -A . PASS chr13 28980036 . T -A . PASS chr13 32954022 . CA/+A C . PASS chr15 59186309 . A -T . PASS chr17 29528406 . C -T . PASS chr17 29563075 . GT/+T G . PASS
now ,i'm confused,what the + or - stand for ? can anybody tell me ,thanks!
I don't really understand the strand problem ? Can you give more details please /command ?