Question

What is the difference between NZ_ and NC_ identifiers at NCBI?

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8.3 years ago

frenchmytoast112 ▴ 10

Hi,

I noted that some of my genomes are names with an NZ_ and other with NC_ identifier. What is the difference between them? Specifically, are NZ_ "complete" genomes?

sequence Assembly next-gen • 8.3k views

ADD COMMENT • link updated 8.3 years ago by keith.hughitt ▴ 280 • written 8.3 years ago by frenchmytoast112 ▴ 10

score 3 · Accepted Answer · 2016-08-28

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8.3 years ago

keith.hughitt ▴ 280

From The NCBI Handbook, ch18: (via this answer)

NC - "Complete genomic molecule, usually reference assembly"

NZ - "Unfinished WGS"

ADD COMMENT • link 8.3 years ago by keith.hughitt ▴ 280

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But how can a genome be NZ_ and have status "complete" at this NCBI website: www.ncbi.nlm.nih.gov/genome/browse/ ?

ADD REPLY • link 8.3 years ago by frenchmytoast112 ▴ 10

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I think that it's beacause NZ- means both complete genomes and unfinished WGS data (https://www.ncbi.nlm.nih.gov/books/NBK21091/table/ch18.T.refseq_accession_numbers_and_mole/?report=objectonly)

ADD REPLY • link 3.9 years ago by saracuesta95 • 0